Role of Oatp2b1 in Drug Absorption and Drug-Drug Interactions
نویسندگان
چکیده
منابع مشابه
The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions.
INTRODUCTION The in vivo fate and effectiveness of a drug depends highly on its absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Organic anion transporting polypeptides (OATPs) are membrane proteins involved in the cellular uptake of various organic compounds, including clinically used drugs. Since OATPs are significant players in drug absorption and distribution, modula...
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ژورنال
عنوان ژورنال: Drug Metabolism and Disposition
سال: 2020
ISSN: 0090-9556,1521-009X
DOI: 10.1124/dmd.119.090316